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Graduate School of Medicine, Chiba University / Health and Disease Omics Center
Professor / DirectorCells accumulate abnormalities in their genomic and epigenomic information, which can lead to diseases like cancer. The epigenome, which involves modifications to the genome, changes due to environmental factors and stress such as aging, infection, and inflammation in somewhat defined manners, resulting in cell fate alteration. Exploring and harnessing the accumulated epigenomic aberrations is a crucial step in elucidating cancer and developing novel cancer treatments.
Recent Topics of Interests:
Cancer risk diagnosis, Integrated omics analysis
Motto in Research or in Life: Insatiable inquiry and challenge
Graduate School of Science, Chiba University
Associate ProfessorGenomic DNA, the blueprint of our cells, is constantly subjected to damage. As this damage accumulates, it can lead to various diseases, including aging, cancer, and autoimmune disorders. But is DNA damage always harmful? In fact, it may play an essential role in the maintenance and evolution of life. My research focuses on the relationship between DNA damage, biological mechanisms, and disease.
Recent Topics of Interest:
1) The Butterfly Effect of DNA Damage: DNA damage triggers unexpected changes that spread throughout the cell, significantly altering chromatin function and RNA dynamics. Understanding this phenomenon may provide insights into how DNA damage influences cell fate.
2) DNA Damage and Immunity: I investigate the impact of DNA damage on immune function.
3) Development of a Test for Genomic Toxicity: I create new methods to determine how chemicals affect genomic DNA.
Motto in Research or in Life:
A series of small steps has the power to change the world.
Hobby / Holiday:
Singing Karaoke, driving, and sleeping