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Future Medicine Education and Research Organization, Chiba University / Chiba University Hospital
Distinguished ProfessorAfter graduating from the Nihon University’s School of Dentistry at Matsudo in 1977, and during the time of the doctoral program in medical sciences at the University of Alabama at Birmingham (UAB) in 1983, I started my significant research career by contributing to the launch of the “Mucosal Immunology” as a scientist at the UAB and the Max Planck Institute for Biology. While pursuing my research career as an immunologist, especially in the advancement of mucosal immunology and vaccinology, I also trained and educated the next-generation physician-scientists, students, and researchers as a professor at UAB, Osaka University and the University of Tokyo, and now University of California San Diego (UCSD) and Chiba University. In addition to my research and academic careers, I also contributed my expertise to leading the Institute of Medical Science as Associate Dean and Dean at the University of Tokyo,
My background as a dentist combined with extensive research experience in the field of Mucosal Immunology makes me exceptionally well qualified to lead and advance the current and future directions of mucosal immunology and mucosal vaccine development. I and my research team has also actively facilitated the development of the next-generation vaccines, the oral and nasal vaccines, which are now in critical pre-clinical and clinical trial stages.
These include efforts in developing practical applications such as “MucoRice,” the rice-based oral vaccine, and the “cationic nanogel” nasal vaccine. Currently, I am dedicated to advancing the practical development of “oral and nasal vaccines” at Chiba University.
Recent Topics of Interest: Mucosal immunology, Mucosal vaccines
Motto in Research or in Life: No problem!! Your dream is your destiny!!
Graduate School of Medicine, Chiba University
ProfessorMy goal is to elucidate the cellular and molecular mechanisms underlying diseases caused by immune system overreactions, such as allergic conditions including bronchial asthma and autoimmune diseases like rheumatoid arthritis. I aim to develop treatments based on these findings.
I am particularly interested in understanding the mechanisms that control T cell activation, which plays a central role in immune system dysregulation, and exploring the epigenetic regulation of immune memory.
Recent Topics of Interest:
(1) Understanding the cellular and molecular mechanisms underlying the development of allergic diseases, including asthma
(2) Investigating the cellular and molecular mechanisms involved in the development of autoimmune diseases such as rheumatoid arthritis and systemic lupus erythematosus
(3) Advancing treatments for allergies and autoimmune diseases through immune memory resetting strategies
Motto in Research or in Life:
Research motto
(1) I prioritize ‘intriguing’: I aim for research that is not only ‘intriguing’ medically but also biologically.
(2) I cherish the unexpected: I consider our hypotheses to be as small as grains of sand in the 4.6 billion years of Earth's history.
Motto in life
(1) I avoid turning down work whenever possible, but as a result, I am finding it increasingly difficult to do what I truly want.
(2) I try not to say “I have no choice" as much as possible; however, as a consequence, there’s a buildup of situations where it just can’t be helped.
(3) I strive not to make enemies, or at least that's my intention.
Hobby / Holiday:
Watching wombat videos, Traveling, especially visiting shrines and temples, Jogging during a trip, Visiting art galleries and museums