Institute for Advanced Academic Research / Graduate School of Medicine, Chiba University
LecturerThe molecular mechanism of carcinogenesis mediated by extrachromosomal DNA (ecDNA) remain largely unknown, despite increasing interest in this area in recent years. Previous studies have identified the presence of ecDNA in virus-associated cancers, where segments of the human and viral genomes are fused to form human-viral hybrid ecDNA (hybrid ecDNA). These studies have also suggested that hybrid ecDNA may play a critical role in tumorigenesis. My current research aims to elucidate the oncogenic functions of hybrid ecDNA by performing multi-omics analyses of clinical specimens and integrating clinical imaging, nutritional information, and other datasets. Through this work, I seek to develop novel therapeutic strategies to overcome virus-associated cancers.
Recent Topics of Interest:
extrachromosomal DNA (ecDNA), Spatial transcriptome analysis, AI
Motto in Research or in Life:
Always strive to stay one step ahead of the status quo
Hobby / Holiday:
Enjoy playing baseball and soccer, appreciating art, and discovering natural wine
